(?—1013)宋澶州衛(wèi)南人。太宗時為天武指揮使。淳化間權(quán)知夏州,尋受詔提轄河東緣邊城池、器甲、芻糧。累官至副都部署,屢破蕃兵。真宗大中祥符初,召為龍神衛(wèi)四廂都指揮使、領(lǐng)登州防御使,出任邠寧環(huán)慶路副都部署兼知邠州。坐事改知懷州。有武略,所至頗著聲績。
工作經(jīng)歷
2012.7- 中國科學院國家數(shù)學與交叉科學中心生物醫(yī)學部 助理研究員 2012.7- 中國科學院數(shù)學與系統(tǒng)科學研究院 助理研究員
主要成就
在Nature子刊、Nucleic Acids Research、Bioinformatics、Briefings in Bioinformatics等國際權(quán)威期刊以第一作者和通訊作者身份發(fā)表生物信息學相關(guān)領(lǐng)域論文18篇,第一作者14篇, 通訊作者10篇,發(fā)表論文目前共被引用302次,參編專著4部,獲得授權(quán)專利1項,曾獲國際網(wǎng)絡(luò)博弈論大會最佳論文獎、中科院數(shù)學院院長獎學金、博時獎學金、永安期貨獎學金、英達獎學金、第四屆世界華人數(shù)學家大會新世界數(shù)學獎、美國數(shù)學建模競賽國際一等獎等榮譽,主持或以骨干身份參與 國家自然科學基金重大研究計劃、國家自然科學基金青年基金等11項重要項目.
著作成果
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA Scientific Reports:2015,5:13186 (SCI 影響因子5.578, nature旗下,獨立作者) Drug–target interaction prediction: databases, web servers and computational models Briefings in Bioinformatics: 2015 ,In press (SCI 影響因子9.617,第一作者和通訊作者) RBMMMDA: predicting multiple types of disease-microRNA associations Scientific Reports:2015,5: 13877 (SCI 5.578, nature旗下,第一作者和通訊作者) Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity Scientific Reports. 2015 5:11338 (SCI 5.578, nature旗下,第一作者和通訊作者) Distributed Image Understanding with Semantic Dictionary and Semantic Expansion Neurocomputing:2015,In press (SCI 2.083) Semi-supervised learning for potential human microRNA-disease associations inference Scientific Reports. 2014,4:5501 (SCI 5.078, nature旗下,被引用10次,第一作者和通訊作者) 2012-2013運籌學學科發(fā)展報告 中國運籌學會.中國科學技術(shù)出版社:,2014 ASDCD: Antifungal Synergistic Drug Combination Database PLOS ONE:2014,9(1): e86499 (SCI 3.73 第一作者). Large Scale Image Understanding with Non-convex Multi-task Learning The 2014 5th International Conference on Game Theory for Networks:2014,Best Paper Award. Novel human lncRNA-disease association inference based on lncRNA expression profiles Bioinformatics:2013,29(20),2617-2624 (SCI 5.323, 2/47 in Mathematical & Computational Biology,被引用12次,第一作者和通訊作者) A computational framework to infer human disease-associated long noncoding RNAs PLOS ONE:2014,9(1): e84408 (SCI 3.73,被引用13次). LncRNADisease: a database for long-non-coding RNA-associated diseases Nucleic Acids Research:2013,41(Database issue),D983--D986 (SCI: 8.026, 26/289 in Biochemistry and Molecular Biology,被引用120次). Drug-Target Interaction Prediction by Random Walk on the Heterogeneous Network Molecular BioSystems:2012,8(7)1970-1978 (SCI 3.825,被引用52次 Top ten most accessed articles),in June 2012;Top 10% of the most highly cited articles published in the latest Impact Factor window (2011-2012), 第一作者). RWRMDA: predicting novel human microRNA-disease associations Molecular BioSystems:2012,8(10),1970-1978 (SCI 3.825, 被引用33次,第一作者). Prediction of disease-related interactions between microRNAs and environmental factors based on a semi-supervised classifier PLoS ONE:2012,7(8),e43425 (SCI 4.092,第一作者,被引用12次,第一作者) A novel candidate disease genes prioritization method based on module partition and rank fusion OMICS: A Journal of Integrative Biology:2010,14 (4),337-356 (SCI 3.17,被引用13次,第一作者和通訊作者). 多階段多目標多部門應(yīng)急決策模型 系統(tǒng)工程理論與實踐:2010,30(11),1977-1985 (EI 0.896,被引用23次,第一作者和通訊作者). NRWRH for drug target prediction The 4th International conference on computational Systems Biology:2010,13,219-226 (ISTP, 第一作者和通訊作者). Modularized random walk with restart for candidate disease genes prioritization Optimization and Systems Biology:2009,11,353-360 (ISTP, 第一作者和通訊作者).
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